glutathione increases in cancer cells the tumor and the liver. Tumor maintain elevated AKR1C1 interacts with STAT3 to
AKR1C1 interacts with STAT3 to increase intracellular glutathione and confers resistance to oxaliplatin in colorectal cancer ScienceDirect Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression: Cancer Cell Glutathione Synthesis in Cancer Cells Biochemistry (Moscow) Springer Nature Link Glutathione overproduction mediates lymphoma initiating cells survival and has a sex dependent effect on lymphomagenesis Cell Death & Disease Involvement of glutathione peroxidases in the occurrence and development of breast cancers Journal of Translational Medicine Springer Nature Link Human cancer associated fibroblasts enhance glutathione levels and antagonize drug induced prostate cancer cell death Cell Death & Disease
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